{\rtf1\deflang1033\deflangfe1033\margl720\margr720\margt360\margb360{\stylesheet{\fs20\lang1033\snext0 Normal;} {\s1\sb240\keepn{\*\pn \pnlvl1\pndec\pnprev1\pnstart1\pnsp144}\b\f0\fs30\lang1033 \sbasedon0\snext0 heading 1;} {\s2\sb200\keepn{\*\pn \pnlvl2\pndec\pnprev1\pnstart1\pnsp144{\pntxtb.}}\b\f0\fs26\lang1033 \sbasedon0\snext0 heading 2;} {\s3\sb180\keepn{\*\pn \pnlvl3\pndec\pnprev1\pnstart1\pnsp144{\pntxtb.}}\b\f0\fs22\lang1033 \sbasedon0\snext0 heading 3;} {\s4\sb160\keepn{\*\pn \pnlvl4\pnucltr\pnprev1\pnstart1\pnsp144{\pntxtb.}}\b\f0\fs22\lang1033 \sbasedon0\snext0 heading 4;} {\s5\sb140\keepn{\*\pn \pnlvl5\pncltr\pnprev1\pnstart1\pnsp144}\b\f0\fs20\lang1033 \sbasedon0\snext0 heading 5;} {\s6\tqc\lang1033\sbasedon0\snext6 footer;} {\*\cs16 \additive\super\sbasedon10 footnote reference;} {\*\cs18 \additive\sbasedon10 page number;}} {\fonttbl{\f0\fnil Times New Roman;}{\f1\fnil Courier New}{\f2005\fnil Courier New;}{\f2010\fnil Wingdings;}{\f2020\fnil Webdings;}{\f2\fnil Arial;}{\f3\fnil Arial;}{\f4\fnil LucidaHandwriting;}{\f5\fnil Symbol;}{\f6\fnil Symbol;}{\f7\fnil Ferdsch;}{\f30\fnil Myriad Cn Semibold;}{\f31\fnil Myriad Roman;}{\f50\fnil Courier New;}{\f51\fnil Times New Roman;}{\f52\fnil Arial;}{\f53\fnil Symbol;}{\f54\fnil Wingdings;}{\f55\fnil Wingdings 2;}{\f56\fnil Wingdings 3;}{\f57\fnil Webdings;}{\f58\fnil Arial Narrow;}{\f59\fnil Arial Unicode MS;}{\f60\fnil Cyberbit;}{\f61\fnil Morningstar 1U Light;}{\f62\fnil Calibri;}} {\colortbl;\red0\green0\blue0;\red127\green0\blue0;\red0\green0\blue255;\red127\green127\blue127;\red0\green51\blue153;\red255\green204\blue0;\red255\green255\blue255;\red246\green244\blue236;\red0\green0\blue0;\red1\green1\blue1;} {\*\bkmkstart filing_1}{\*\bkmkend filing_1}{\*\bkmkstart doc_1_1}{\*\bkmkend doc_1_1}\par\pard\plain\brdrb\brdrs\cf1\f51\fs2\ql \~\par\pard\plain\cf1\f51\fs20\b\qc \~\par\pard\plain\cf1\f51\fs36\b\qc UNITED STATES\par\pard\plain\cf1\f51\fs36\b\qc SECURITIES AND EXCHANGE COMMISSION\par\pard\plain\cf1\f51\fs20\b\qc Washington, D.C. 20549\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\f0\fs4\par\pard\plain\f0\fs2\brdrt\brdrs\brdrw15\brdrcf2\brdrsp0\par\pard\plain\f0\fs4\par\par\pard\plain\cf1\f51\fs20\qc \~\par\pard\plain\cf1\f51\fs36\b\qc FORM\~8-K\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs24\b\qc CURRENT REPORT\par\pard\plain\cf1\f51\fs24\b\qc Pursuant to Section\~13 or 15(d)\~of\par\pard\plain\cf1\f51\fs24\b\qc The Securities Exchange Act of 1934\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc Date of Report (Date of earliest event reported)\par\pard\plain\cf1\f51\fs20\b\qc September\~7, 2018\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\f0\fs4\par\pard\plain\f0\fs2\brdrt\brdrs\brdrw15\brdrcf2\brdrsp0\par\pard\plain\f0\fs4\par\par\pard\plain\cf1\f51\fs20\qc \~\par\pard\plain\cf1\f51\fs36\b\qc VIVUS,\~INC.\par\pard\plain\cf1\f51\fs20\qc (Exact name of registrant as specified in its charter)\par\pard\plain\cf1\f51\fs20\ql \~ \par\pard\plain {\trowd\trqc\cellx3456\clvertalb\cellx3672\cellx7128\clvertalb\cellx7343\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\b\qc Delaware\cell\pard\plain\intbl\cf1\f51\fs2\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\b\qc 001-33389\cell\pard\plain\intbl\cf1\f51\fs2\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\b\qc 94-3136179\cell{ {\trowd\trqc\cellx3456\clvertalb\cellx3672\cellx7128\clvertalb\cellx7343\cellx10800\trrh248\row}}} {\trowd\trqc\cellx3456\clvertalb\cellx3672\cellx7128\clvertalb\cellx7343\cellx10800\trrh495 \pard\plain\intbl\cf1\f51\fs20\qc (State or other jurisdiction of \par\pard\plain\intbl\fs16\pard\plain\intbl\cf1\f51\fs20\qc incorporation)\cell\pard\plain\intbl\cf1\f51\fs2\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\qc (Commission File Number)\cell\pard\plain\intbl\cf1\f51\fs2\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\qc (IRS Employer \par\pard\plain\intbl\fs16\pard\plain\intbl\cf1\f51\fs20\qc Identification No.)\cell{ {\trowd\trqc\cellx3456\clvertalb\cellx3672\cellx7128\clvertalb\cellx7343\cellx10800\trrh495\row}}}\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\b\qc 900 E. HAMILTON AVENUE, SUITE 550\par\pard\plain\cf1\f51\fs20\b\qc CAMPBELL, CA 95008\par\pard\plain\cf1\f51\fs20\qc (Address of principal executive offices, including zip code)\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\b\qc (650) 934-5200\par\pard\plain\cf1\f51\fs20\qc (Registrant\u8217?s telephone number, including area code)\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\b\qc N/A\par\pard\plain\cf1\f51\fs20\qc (Former name or former address, if changed since last report)\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql Check the appropriate box below if the Form\~8-K filing is intended to simultaneously satisfy the filing obligation of the\plain\cf1\f51\fs20\ql registrant under any of the following provisions (see General Instruction A.2. below):\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\li308\fi-308\cf1\f54\fs20\ql o\plain\li308\cf1\f51\fs20\ql Written communications pursuant to Rule\~425 under the Securities Act (17 CFR 230.425)\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\li308\fi-308\cf1\f54\fs20\ql o\plain\li308\cf1\f51\fs20\ql Soliciting material pursuant to Rule\~14a-12 under the Exchange Act (17 CFR 240.14a-12)\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\li308\fi-308\cf1\f54\fs20\ql o\plain\li308\cf1\f51\fs20\ql Pre-commencement communications pursuant to Rule\~14d-2(b)\~under the Exchange Act (17 CFR 240.14d-2(b))\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\li308\fi-308\cf1\f54\fs20\ql o\plain\li308\cf1\f51\fs20\ql Pre-commencement communications pursuant to Rule\~13e-4(c)\~under the Exchange Act (17 CFR 240.13e-4(c))\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql Indicate by check mark whether the registrant is an emerging growth company as defined in Rule\~405 of the Securities Act of\plain\cf1\f51\fs20\ql 1933 (\u167?230.405 of this chapter) or Rule\~12b-2 of the Securities Exchange Act of 1934 (\u167?240.12b-2 of this chapter).\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql Emerging growth company\~\~\~\plain\cf1\f54\fs20\ql o\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for\plain\cf1\f51\fs20\ql complying with any new or revised financial accounting standards provided pursuant to Section\~13(a)\~of the Exchange Act.\~\~\~\plain\cf1\f54\fs20\ql o\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\brdrb\brdrs\cf1\f51\fs2\ql \~\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\f0\fs4\par\pard\plain\f0\fs2\brdrt\brdrs\brdrw15\brdrcf2\brdrsp0\par\pard\plain\f0\fs4\par \page \par\pard\plain\fs16\par\pard\plain\cf1\f51\fs20\ql \~{\*\bkmkstart part_1_2_1}{\*\bkmkend part_1_2_1}{\*\bkmkstart item_1_37_1}{\*\bkmkend item_1_37_1}\par\pard\plain\cf1\f51\fs20\b\ql Item 3.03. Material Modification to Rights of Security Holders.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql To the extent required by Item 3.03 of Form\~8-K, the information set forth below under Item 5.03 of this Current Report on\plain\cf1\f51\fs20\ql Form\~8-K is incorporated herein by reference.\par\pard\plain\cf1\f51\fs20\ql \~{\*\bkmkstart part_1_2_2}{\*\bkmkend part_1_2_2}{\*\bkmkstart item_1_42_1}{\*\bkmkend item_1_42_1}\par\pard\plain\cf1\f51\fs20\b\ql Item 5.03. Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql On September\~7, 2018, effective as of 12:01 a.m.\~Eastern Time on September\~10, 2018, VIVUS,\~Inc. (the\plain\cf1\f51\fs20\ql \u8220?Company\u8221?) filed a Restated Certificate of Incorporation (the \u8220?Certificate\u8221?) with the Delaware\plain\cf1\f51\fs20\ql Secretary of State to effect the 1-for-10 reverse stock split of the Company\u8217?s common stock.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql The full text of the Certificate is attached as Exhibit\~3.1 to this Current Report on Form\~8-K and is incorporated herein by\plain\cf1\f51\fs20\ql reference.\par\pard\plain\cf1\f51\fs20\ql \~{\*\bkmkstart part_1_2_3}{\*\bkmkend part_1_2_3}{\*\bkmkstart item_1_45_1}{\*\bkmkend item_1_45_1}\par\pard\plain\cf1\f51\fs20\b\ql Item 7.01. Regulation FD Disclosure.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql On September\~10, 2018, the Company issued a press release announcing the Company\u8217?s 1-for-10 reverse stock split. A\plain\cf1\f51\fs20\ql copy of the press release is furnished herewith as Exhibit\~99.1.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql The information in this Current Report on Form\~8-K under Item 7.01, including the accompanying press release, shall not be\plain\cf1\f51\fs20\ql deemed \u8220?filed\u8221? for purposes of Section\~18 of the Securities Exchange Act of 1934, as amended, nor shall it be\plain\cf1\f51\fs20\ql deemed incorporated by reference in any filing under the Securities Act of 1933, as amended, except as shall be expressly set\plain\cf1\f51\fs20\ql forth by reference to such filing.\par\pard\plain\cf1\f51\fs20\ql \~{\*\bkmkstart part_1_2_4}{\*\bkmkend part_1_2_4}{\*\bkmkstart item_1_47_1}{\*\bkmkend item_1_47_1}\par\pard\plain\cf1\f51\fs20\b\ql Item 9.01. Financial Statements and Exhibits.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql (d)\~Exhibits.\par\pard\plain\cf1\f51\fs20\ql \~ \par\pard\plain {\trowd\clbrdrb\brdrs\brdrcf1\clvertalb\cellx1080\clvertalb\cellx1403\clbrdrb\brdrs\brdrcf1\clvertalb\cellx10800\trrh198 \pard\plain\intbl\cf1\f51\fs16\b\ql Exhibit\~No.\~\cell\pard\plain\intbl\cf1\f51\fs2\b\qc \~\cell\pard\plain\intbl\cf1\f51\fs16\b\qc Description\cell{ {\trowd\clbrdrb\brdrs\brdrcf1\clvertalb\cellx1080\clvertalb\cellx1403\clbrdrb\brdrs\brdrcf1\clvertalb\cellx10800\trrh198\row}}} {\trowd\cellx1080\clvertalb\cellx1403\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql 3.1\cell\pard\plain\intbl\cf1\f51\fs2\ql \~\cell\pard\plain\intbl\ul{\field{\*\fldinst HYPERLINK \\l "exhibit3_1_024625_12448828" }{\*\fldrslt\cf3\f51\fs20\ql Restated Certificate of Incorporation of VIVUS,\~Inc., as amended and restated through September\~10, 2018}}\cell{ {\trowd\cellx1080\clvertalb\cellx1403\cellx10800\trrh248\row}}} {\trowd\cellx1080\clvertalb\cellx1403\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql 99.1\cell\pard\plain\intbl\cf1\f51\fs2\ql \~\cell\pard\plain\intbl\ul{\field{\*\fldinst HYPERLINK \\l "exhibit99_1_030308_12448828" }{\*\fldrslt\cf3\f51\fs20\ql Press Release dated September\~10, 2018}}\cell{ {\trowd\cellx1080\clvertalb\cellx1403\cellx10800\trrh248\row}}}\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc 2{\*\bkmkstart pb_2_024722_3773_12448828}{\*\bkmkend pb_2_024722_3773_12448828}\par\pard\plain\f0\fs4\par\pard\plain\f0\fs2\brdrt\brdrs\brdrw15\brdrcf2\brdrsp0\par\pard\plain\f0\fs4\par \page \par\pard\plain\fs16\par\pard\plain\cf1\f51\fs20\ql \~{\*\bkmkstart part_1_2_5}{\*\bkmkend part_1_2_5}\par\pard\plain\cf1\f51\fs20\b\qc SIGNATURES\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its\plain\cf1\f51\fs20\ql behalf by the undersigned hereunto duly authorized.\par\pard\plain\cf1\f51\fs20\ql \~ \par\pard\plain {\trowd\cellx5400\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs2\b\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\b\ql VIVUS,\~INC.\cell{ {\trowd\cellx5400\cellx10800\trrh248\row}}} {\trowd\cellx5400\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\b\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\b\ql \~\cell{ {\trowd\cellx5400\cellx10800\trrh248\row}}} {\trowd\cellx5400\clbrdrb\brdrs\brdrcf1\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs2\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql /s/ John L. Slebir\cell{ {\trowd\cellx5400\clbrdrb\brdrs\brdrcf1\cellx10800\trrh248\row}}} {\trowd\cellx5400\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs2\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql John L. Slebir\cell{ {\trowd\cellx5400\cellx10800\trrh248\row}}} {\trowd\cellx5400\cellx10800\trrh495 \pard\plain\intbl\cf1\f51\fs2\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql Senior Vice President, Business Development and General\plain\intbl\cf1\f51\fs20\ql Counsel\cell{ {\trowd\cellx5400\cellx10800\trrh495\row}}} {\trowd\cellx5400\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql Date: September\~10, 2018\cell\pard\plain\intbl\cf1\f51\fs2\ql \~\cell{ {\trowd\cellx5400\cellx10800\trrh248\row}}}\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc 3{\*\bkmkstart pb_3_024740_7056_12448828}{\*\bkmkend pb_3_024740_7056_12448828}\par\pard\plain\f0\fs4\par\pard\plain\f0\fs2\brdrt\brdrs\brdrw15\brdrcf2\brdrsp0\par\pard\plain\f0\fs4\par \page{\*\bkmkstart doc_1_2}{\*\bkmkend doc_1_2}\par\pard\plain\cf1\f51\fs20\b\qr Exhibit 3.1{\*\bkmkstart exhibit3_1_024625_12448828}{\*\bkmkend exhibit3_1_024625_12448828}\par\pard\plain\cf1\f51\fs20\qc \~\par\pard\plain\cf1\f51\fs20\qc AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc VIVUS,\~INC.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~I\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql The name of the corporation is VIVUS,\~Inc. (the \u8220?Corporation\u8221?).\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~II\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql The address of the Corporation\u8217?s registered office in the State of Delaware is 1209 Orange Street, City of\plain\cf1\f51\fs20\ql Wilmington, County of New Castle, Delaware 19801.\~ The name of its registered agent at such address is The Corporation Trust\plain\cf1\f51\fs20\ql Company.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~III\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql The purpose of the Corporation is to engage in any lawful act or activity for which corporations may be organized under\plain\cf1\f51\fs20\ql the General Corporation Law of Delaware.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~IV\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql The Corporation is authorized to issue two classes of shares of stock to be designated, respectively, Common Stock, $0.001\plain\cf1\f51\fs20\ql par value, and Preferred Stock, $0.001 par value.\~ The total number of shares that the Corporation is authorized to issue is\plain\cf1\f51\fs20\ql 205,000,000 shares.\~ The number of shares of Common Stock authorized is 200,000,000.\~ The number of shares of Preferred\plain\cf1\f51\fs20\ql Stock authorized is 5,000,000.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql Upon the filing of the Amended and Restated Certificate of Incorporation on May\~22, 1997, each one outstanding share of\plain\cf1\f51\fs20\ql Common Stock was subdivided and converted into two shares of Common Stock.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql As of 12:01 AM (eastern time) on September\~10, 2018 (the \u8220?Effective Time\u8221?), each ten (10)\~shares of\plain\cf1\f51\fs20\ql Common Stock issued and outstanding at such time shall be combined into one (1)\~share of Common Stock (the \u8220?Reverse\plain\cf1\f51\fs20\ql Stock Split\u8221?). The par value of the Common Stock following the Reverse Stock Split shall remain $0.001 per share. No\plain\cf1\f51\fs20\ql fractional shares will be issued in connection with the Reverse Stock Split. Stockholders of record who otherwise would be\plain\cf1\f51\fs20\ql entitled to receive fractional shares will be entitled to the rounding up of their fractional share to the nearest whole share. Each\plain\cf1\f51\fs20\ql certificate that immediately prior to the Effective Time represented shares of Common Stock (an \u8220?Old Certificate\u8221?)\plain\cf1\f51\fs20\ql shall thereafter represent that number of shares of Common Stock into which the shares of Common Stock represented by the\plain\cf1\f51\fs20\ql Old Certificate shall have been combined, subject to the adjustment of fractional share interests as described above.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql The Preferred Stock may be issued from time to time in one or more series pursuant to a resolution or resolutions providing\plain\cf1\f51\fs20\ql for such issue duly adopted by the board of directors (authority to do so being hereby expressly vested in the board).\~ The board\plain\cf1\f51\fs20\ql of directors is further authorized to determine or alter the rights, preferences, privileges and restrictions granted to or imposed\plain\cf1\f51\fs20\ql upon any wholly unissued series of Preferred Stock and to fix the number of shares of any series of Preferred Stock and the\plain\cf1\f51\fs20\ql designation of any such series of Preferred Stock.\~ The board of directors, within the limits and restrictions stated in any\plain\cf1\f51\fs20\ql resolution or resolutions of the board of directors originally fixing the number of shares constituting any series, may increase or\plain\cf1\f51\fs20\ql decrease (but not below the number of shares in any such series then outstanding) the number of shares of any series subsequent\plain\cf1\f51\fs20\ql to the issue of shares of that series.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql The authority of the board of directors with respect to each such class or series shall include, without limitation of the\plain\cf1\f51\fs20\ql foregoing, the right to determine and fix:\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\f0\fs4\par\pard\plain\f0\fs2\brdrt\brdrs\brdrw15\brdrcf2\brdrsp0\par\pard\plain\f0\fs4\par \page \par\pard\plain\fs16\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql (a)\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql the distinctive designation of such class or series and the number of shares to constitute such class or series;\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql (b)\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql the rate at which dividends on the shares of such class or series shall be declared and paid, or set aside for payment,\plain\cf1\f51\fs20\ql whether dividends at the rate so determined shall be cumulative or accruing, and whether the shares of such class or series shall\plain\cf1\f51\fs20\ql be entitled to any participating or other dividends in addition to dividends at the rate so determined, and if so, on what terms;\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql (c)\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql the right or obligation, if any, of the corporation to redeem shares of the particular class or series of Preferred Stock\plain\cf1\f51\fs20\ql and, if redeemable, the price, terms and manner of such redemption;\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql (d)\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql the special and relative rights and preferences, if any, and the amount or amounts per share, which the shares of such\plain\cf1\f51\fs20\ql class or series of Preferred Stock shall be entitled to receive upon any voluntary or involuntary liquidation, dissolution or winding\plain\cf1\f51\fs20\ql up of the Corporation;\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql (e)\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql the terms and conditions, if any, upon which shares of such class or series shall be convertible into, or exchangeable\plain\cf1\f51\fs20\ql for, shares of capital stock of any other class or series, including the price or prices or the rate or rates of conversion or exchange\plain\cf1\f51\fs20\ql and the terms of adjustment, if any;\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql (f)\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql the obligation, if any, of the corporation to retire, redeem or purchase shares of such class or series pursuant to a\plain\cf1\f51\fs20\ql sinking fund or fund of a similar nature or otherwise, and the terms and conditions of such obligation;\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql (g)\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql voting rights, if any, on the issuance of additional shares of such class or series or any shares of any other class or\plain\cf1\f51\fs20\ql series of Preferred Stock;\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql (h)\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql limitations, if any, on the issuance of additional shares of such class or series or any shares of any other class or\plain\cf1\f51\fs20\ql series of Preferred Stock; and\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql (i)\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql such other preferences, powers, qualifications, special or relative rights and privileges thereof as the board of directors\plain\cf1\f51\fs20\ql of the corporation, acting in accordance with this Amended and Restated Certificate of Incorporation, may deem advisable and\plain\cf1\f51\fs20\ql are not inconsistent with law and the provisions of this Amended and Restated Certificate of Incorporation.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~V\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql The Corporation reserves the right to amend, alter, change, or repeal any provision contained in this Amended and Restated\plain\cf1\f51\fs20\ql Certificate of Incorporation, in the manner now or hereafter prescribed by statute, and all rights conferred upon the stockholders\plain\cf1\f51\fs20\ql herein are granted subject to this right.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~VI\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql The Corporation is to have perpetual existence.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~VII\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql 1.\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql Limitation of Liability.\~ To the fullest extent permitted by the General Corporation Law of the State of Delaware as\plain\cf1\f51\fs20\ql the same exists or as may hereafter be amended, a director of the Corporation shall not be personally liable to the Corporation or\plain\cf1\f51\fs20\ql its stockholders for monetary damages for breach of fiduciary duty as a director.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql 2.\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql Indemnification.\~ The Corporation may indemnify to the fullest extent permitted by law any person made or\plain\cf1\f51\fs20\ql threatened to be made a party to an action or proceeding, whether criminal, civil, administrative or investigative, by reason of the\plain\cf1\f51\fs20\ql fact that such person or his or her testator or intestate is or was a director, officer or employee of the Corporation, or any\plain\cf1\f51\fs20\ql predecessor of the Corporation, or serves or served at any other enterprise as a director, officer or employee at the request of the\plain\cf1\f51\fs20\ql Corporation or any predecessor to the Corporation.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\f0\fs4\par\pard\plain\f0\fs2\brdrt\brdrs\brdrw15\brdrcf2\brdrsp0\par\pard\plain\f0\fs4\par \page \par\pard\plain\fs16\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql 3.\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql Amendments.\~ Neither any amendment nor repeal of this Article\~VII, nor the adoption of any provision of the\plain\cf1\f51\fs20\ql Amended and Restated Certificate of Incorporation inconsistent with this Article\~VII, shall eliminate or reduce the effect of this\plain\cf1\f51\fs20\ql Article\~VII, in respect of any matter occurring, or any action or proceeding accruing or arising or that, but for this Article\~VII,\plain\cf1\f51\fs20\ql would accrue or arise, prior to such amendment, repeal, or adoption of an inconsistent provision.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~VIII\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql In the event any shares of Preferred Stock shall be redeemed or converted pursuant to the terms hereof, the shares so\plain\cf1\f51\fs20\ql converted or redeemed shall not revert to the status of authorized but unissued shares, but instead shall be canceled and shall not\plain\cf1\f51\fs20\ql be re-issuable by the Corporation.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~IX\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql Holders of stock of any class or series of this corporation shall not be entitled to cumulate their votes for the election of\plain\cf1\f51\fs20\ql directors or any other matter submitted to a vote of the stockholders, unless such cumulative voting is required pursuant to\plain\cf1\f51\fs20\ql Sections 2115 and/or 301.5 of the California Corporations Code, in which event each such holder shall be entitled to as many\plain\cf1\f51\fs20\ql votes as shall equal the number of votes which (except for this provision as to cumulative voting) such holder would be entitled\plain\cf1\f51\fs20\ql to cast for the election of directors with respect to his shares of stock multiplied by the number of directors to be elected by him,\plain\cf1\f51\fs20\ql and the holder may cast all of such votes for a single director or may distribute them among the number of directors to be voted\plain\cf1\f51\fs20\ql for, or for any two or more of them as such holder may see fit, so long as the name of the candidate for director shall have been\plain\cf1\f51\fs20\ql placed in nomination prior to the voting and the stockholder, or any other holder of the same class or series of stock, has given\plain\cf1\f51\fs20\ql notice at the meeting prior to the voting of the intention to cumulate votes.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~X\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql 1.\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql Number of Directors.\~ The number of directors which constitutes the whole Board of Directors of the corporation shall\plain\cf1\f51\fs20\ql be designated in the Bylaws of the corporation.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql 2.\plain\cf1\f51\fs6\ql \~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\~\plain\cf1\f51\fs20\ql Election of Directors.\~ Elections of directors need not be by written ballot unless the Bylaws of the corporation shall\plain\cf1\f51\fs20\ql so provide.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~XI\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql In furtherance and not in limitation of the powers conferred by statute, the Board of Directors is expressly authorized to\plain\cf1\f51\fs20\ql make, alter, amend or repeal the Bylaws of the corporation.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~XII\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql No action shall be taken by the stockholders of the corporation except at an annual or special meeting of the stockholders\plain\cf1\f51\fs20\ql called in accordance with the Bylaws of the corporation, and no action shall be taken by the stockholders by written consent.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\qc ARTICLE\~XIII\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\fi484\cf1\f51\fs20\ql Meetings of stockholders may be held within or without the State of Delaware, as the Bylaws may provide.\~ The books of\plain\cf1\f51\fs20\ql the Corporation may be kept (subject to any provision contained in the statutes) outside of the State of Delaware at such place or\plain\cf1\f51\fs20\ql places as may be designated from time to time by the Board of Directors or in the Bylaws of the Corporation.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\f0\fs4\par\pard\plain\f0\fs2\brdrt\brdrs\brdrw15\brdrcf2\brdrsp0\par\pard\plain\f0\fs4\par \page{\*\bkmkstart doc_1_3}{\*\bkmkend doc_1_3}\par\pard\plain\cf1\f51\fs20\b\qr Exhibit 99.1{\*\bkmkstart exhibit99_1_030308_12448828}{\*\bkmkend exhibit99_1_030308_12448828}\par\pard\plain\cf1\f51\fs20\ql \~\par\ql{\*\shppict{\pict\pngblip\picw144\pich82\picscalex75\picscaley75\bliptag-5686741027 {\*\blipuid 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\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\b\qc VIVUS Announces 1-for-10 Reverse Stock Split\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql CAMPBELL, Calif., September\~10, 2018 (GLOBE NEWSWIRE) \u8212? VIVUS,\~Inc. (Nasdaq:VVUS) (the\plain\cf1\f51\fs20\ql \u8220?Company\u8221?), a biopharmaceutical company, announced today that the Company\u8217?s stockholders approved a\plain\cf1\f51\fs20\ql reverse stock split. Effective September\~10, 2018, the Company will enact a 1-for-10 reverse stock split of its common stock\plain\cf1\f51\fs20\ql with shares trading on a split-adjusted basis on September\~11, 2018.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql \u8220?The 1-for-10 ratio was determined following an analysis of over 700 companies that effected a reverse split from 1998\plain\cf1\f51\fs20\ql to 2018. Based on this analysis, we determined that the 1-for-10 ratio would position VIVUS with the appropriate liquidity\plain\cf1\f51\fs20\ql associated with listing shares on a major U.S. exchange and is critical for the continued execution of our strategic plan to return\plain\cf1\f51\fs20\ql VIVUS to profitability and establish a sustainable business that creates value for stockholders and patients,\u8221? said\~John\plain\cf1\f51\fs20\ql Amos, Chief Executive Officer at VIVUS. \u8220?In addition, this reverse stock split is a necessary step to allow VIVUS to\plain\cf1\f51\fs20\ql meet the requirements for continued listing on The Nasdaq Stock Market.\u8221?\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql Stockholders approved the reverse stock split at the 2018 Annual Meeting of Stockholders on September\~7, 2018, and on the\plain\cf1\f51\fs20\ql same day, VIVUS\u8217? Board of Directors approved the implementation of the reverse stock split and the ratio of 1-for-10.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql Shares of VIVUS common stock will trade on a post-split basis beginning on September\~11, 2018. The Company\u8217?s ticker\plain\cf1\f51\fs20\ql symbol, VVUS, will remain unchanged. The new CUSIP number for VIVUS\u8217? common stock post-reverse split will be\plain\cf1\f51\fs20\ql 928551 308.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql At the effective time of the reverse stock split, every 10 shares of VIVUS issued and outstanding common stock will\plain\cf1\f51\fs20\ql automatically be combined and converted into 1 issued and outstanding share of common stock without any change in the par\plain\cf1\f51\fs20\ql value of the shares. This will reduce the outstanding shares of common stock of VIVUS from approximately 106 million to\plain\cf1\f51\fs20\ql approximately 10.6 million. Proportional adjustments will also be made to the shares issuable in connection with VIVUS\u8217?\plain\cf1\f51\fs20\ql outstanding stock options, restricted stock units, warrants and convertible securities.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql Proportionate voting rights and other rights of stockholders will not be affected by the reverse stock split, other than as a result\plain\cf1\f51\fs20\ql of the rounding up of fractional shares. Please direct any questions you might have regarding the reverse stock split to your\plain\cf1\f51\fs20\ql broker or the Company\u8217?s stock transfer agent, Computershare Investor Services, by calling 877-373-6374 (Toll Free) or\plain\cf1\f51\fs20\ql +1 (781) 575-3120 (Toll).\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\f0\fs4\par\pard\plain\f0\fs2\brdrt\brdrs\brdrw15\brdrcf2\brdrsp0\par\pard\plain\f0\fs4\par \page \par\pard\plain\fs16\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\b\ql About VIVUS\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql VIVUS is a biopharmaceutical company committed to the development and commercialization of innovative therapies that focus\plain\cf1\f51\fs20\ql on advancing treatments for patients with serious unmet medical needs. For more information about the Company, please visit\plain\cf1\f51\fs20\ql www.vivus.com.\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\b\ql Forward-Looking Statements\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\i\ql Certain statements in this press release are forward-looking within the meaning of the Private Securities Litigation Reform Act\plain\cf1\f51\fs20\i\ql of 1995 and are subject to risks, uncertainties and other factors, including risks and uncertainties related to potential change in\plain\cf1\f51\fs20\i\ql our business strategy to enhance long-term stockholder value; risks and uncertainties related to our ability to address or\plain\cf1\f51\fs20\i\ql potentially reduce the outstanding balance of our convertible notes due in 2020; risks and uncertainties related to our expected\plain\cf1\f51\fs20\i\ql future revenues, operations and expenditures; risks and uncertainties related to our ability to identify and acquire development\plain\cf1\f51\fs20\i\ql and cash flow generating assets; risks and uncertainties related to the timing of initiation and completion of the post-approval\plain\cf1\f51\fs20\i\ql clinical studies required as part of the approval of Qsymia by the U.S. Food and Drug Administration, or FDA; risks and\plain\cf1\f51\fs20\i\ql uncertainties related to the response from FDA to any data and/or information relating to post-approval clinical studies\plain\cf1\f51\fs20\i\ql required for Qsymia; risks and uncertainties related to our ability to work with FDA to significantly reduce or remove the\plain\cf1\f51\fs20\i\ql requirements of the clinical post-approval cardiovascular outcomes trial, or CVOT; and risks and uncertainties related to our\plain\cf1\f51\fs20\i\ql ability to regain and retain compliance with Nasdaq listing requirements. These risks and uncertainties could cause actual results\plain\cf1\f51\fs20\i\ql to differ materially from those referred to in these forward-looking statements. The reader is cautioned not to rely on these\plain\cf1\f51\fs20\i\ql forward-looking statements. Investors should read the risk factors set forth in VIVUS\u8217? Form\~10-K for the year ended\plain\cf1\f51\fs20\i\ql December\~31, 2017 as filed on March\~14, 2018, and as amended by the Form\~10-K/A filed on April\~26, 2018, and periodic\plain\cf1\f51\fs20\i\ql reports filed with the Securities and Exchange Commission. VIVUS does not undertake an obligation to update or revise any\plain\cf1\f51\fs20\i\ql forward-looking statements.\par\pard\plain\cf1\f51\fs20\ql \~ \par\pard\plain {\trowd\cellx5454\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\b\ql VIVUS,\~Inc.\cell\pard\plain\intbl\cf1\f51\fs20\b\ql Investor Relations: Lazar Partners\cell{ {\trowd\cellx5454\cellx10800\trrh248\row}}} {\trowd\cellx5454\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql Mark Oki\cell\pard\plain\intbl\cf1\f51\fs20\ql David Carey\cell{ {\trowd\cellx5454\cellx10800\trrh248\row}}} {\trowd\cellx5454\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql Chief Financial Officer\cell\pard\plain\intbl\cf1\f51\fs20\ql Managing Director\cell{ {\trowd\cellx5454\cellx10800\trrh248\row}}} {\trowd\cellx5454\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql oki@vivus.com\cell\pard\plain\intbl\cf1\f51\fs20\ql dcarey@lazarpartners.com\cell{ {\trowd\cellx5454\cellx10800\trrh248\row}}} {\trowd\cellx5454\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql 650-934-5200\cell\pard\plain\intbl\cf1\f51\fs20\ql 212-867-1768\cell{ {\trowd\cellx5454\cellx10800\trrh248\row}}}\pard\plain\cf1\f51\fs20\qc \~\par\pard\plain\f0\fs4\par\pard\plain\f0\fs2\brdrt\brdrs\brdrw15\brdrcf2\brdrsp0\par\pard\plain\f0\fs4\par}